Eukaryotic antisense ahead of its time

Rousseau's "social contract": contracting ahead of its time?

I. Electronic Voting Systems—Is Brazil Ahead of its Time?

The first article, by Professor Pedro Rezende of the University of Brasilia, describes the political context for the introduction of voter-verifiable paper ballots to their DRE (direct-record electronic, or touch-screen) voting machines for their 2002 elections. Rezende argues that many of the criticisms levelled against voter-verifiable paper ballots, such as the criticism that voter-verifiabl...

Comment on “Ahead of Its Time? Reflecting on New Zealand’s Pharmac Following its 20th Anniversary”

We appreciated Robin Gauld’s assessment of PHARMAC’s role in New Zealand’s medicines funding, published in PharmacoEconomics [1]. The article [1] reflects PHARMAC’s (New Zealand’s Pharmaceutical Management Agency) attempts to achieve in New Zealand the best health outcomes from pharmaceuticals within available funding [2–4]. We would like, however, to clarify a common and easily made assumption...

The SHAPE guideline: ahead of its time or just in time?

In 2006, a grass roots movement called SHAPE (Screening for Heart Attack Prevention and Education) published a novel practice guideline for cardiovascular screening in the asymptomatic at-risk population. It suggested the use of noninvasive tests for subclinical atherosclerosis in cardiovascular risk assessment to target intensified preventive care to those at highest risk. The SHAPE guideline ...

Malcolm MacLean, Jr.: Ahead of His Time and Ahead of Our Time